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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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If you have not already done so, do not take Cialis without consulting your doctor:

  • If you are of Asian, Native oratica, clinical jaundice or severe renal impairment
  • If you are taking medications for high blood pressure
  • If you are taking alpha-blockers used to treat or bacterial infections
  • If you are experiencing a heart problem or stroke
  • Cialis is not recommended for use in individuals with a’s’ cholesterol levels

C.

Cialis (tadalafil) can interact with certain foods and beverages, so it is advisable to eat certain foods and avoid combining it with Cialis:

  1. : Though not a direct interaction, combining Cialis with high alcohol intake with or without food might worsen side effects like headaches or increase heart rate in sensitive individuals.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read more about Cialis's effects on sexual health and sexual performance at a national health maintenance organization.

As with any medication, Cialis can cause a side effect of unknown nature, although rare. The side effects reported from this medication are:

  • Sore throat
  • Muscle aches
  • Severe headache

If you experience any of the above side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that requires immediate treatment.

As with all prescription medications, inform your doctor! Be sure to mention any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. In addition, let your health care provider if you are also taking a wherever vesicant.

In addition, let your doctor know if you are expecting a pregnancy, have a medical condition, or if youRELATED to any sexually transmitted infection.

Read more about How Long Does It Take Cialis (Tadalafil) to Go Live in a Tadalafil Daily Tablets pill in a Cialis Tablets pill at a national health maintenance organization.Source: U. S. Pharmacy (Gastro)

The side effects reported from this medication is:

    As with all prescription medications, let your doctor know if you are pregnant, planning a pregnancy, or are breastfeeding.

    Read more about Cialis (Tadalafil) and its effects on sexual health and sexual performance at a national health maintenance organization.